Pre-built ADME-Tox

Several ADME and Toxicity models built on carefully curated data are available in Sarchitect. The Strand Models are open as well – they come packaged with structures and data for training set, accuracies, the model algorithm and parameters.

ADME Models - truPK

• Plasma Protein Binding
• Bioavailability
• Rate of Absorption
• Volume of Distribution
• Elimination Half-life
• Aqueous Solubility
• BBB

Toxicity Models - truTox

• hERG Channel Binding (Cardiotox)
• Mouse Carcinogenicity (Male & Female)
• Rat Carcinogenicity (Male & Female)
• Ames Mutagenicity

Read the Tech Note on Strand Pre-built Models